Background/Objectives: Genetic overlap between any ischaemic stroke (AIS) and coronary artery disease (CAD) can obscure associations less closely tied to coronary risk. We aimed to separate coronary-shared from residual AIS genetic effects. Methods: We applied GWAS-by-subtraction to GIGASTROKE AIS and UK Biobank/CARDIo...
In astrocytes after TBI, VIM and LGALS3 modulate migration and apoptotic signaling, representing candidate molecular markers and potential therapeutic targets for secondary brain injury that warrant further validation.
Bin-Yang Wang, Yu-Xue Wang, Wen Cao et al.· Neuroscience· 0 citations
This work synthesizes current evidence on the signaling architecture underlying targeted therapy across breast cancer subtypes and proposes a four-layer network topology model of resistance integrating receptor tyrosine kinase reprogramming, epigenetic plasticity coupled with tumor microenvironment (TME) co-evolution,...
Yadong Wang, Maona Zhang, Xuefang Zhang et al.· Critical reviews in oncology...· 1 citation
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