Yu-Yang Gao

Rumen and colon-centered microbiota-liver interactions associated with bile acid-related metabolic regulation in sheep

Background Ruminant gastrointestinal microbiota are spatially heterogeneous, yet whether the rumen microbiota contributes to bile acid-related gut–liver associations beyond its local fermentative role remains unclear. Here, paired rumen, ileum, and colon microbiota were integrated with liver transcriptomic data, blood...