A monoclonal antibody against CD3ε enables characterization of T cell activation and metabolic reprogramming in Chinese seabass (Lateolabrax maculatus).
T cells are essential components of adaptive immunity, while CD3ε, a key subunit of the T-cell receptor (TCR)-CD3 complex, serves as an important marker for T-cell identification and plays a critical role in TCR-mediated activation. However, the scarcity of monoclonal antibody (mAb) against CD3ε from teleosts has hinde...