Author

Yu-Zhang Wu

2 papers indexed here

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Review Open access Oct 2026

Epigenetic regulation of humoral immunity: molecular mechanisms, diseases and therapeutic targets

Humoral immunity, a fundamental branch of adaptive immunity, relies on B lymphocytes and the antibodies they produce to eliminate extracellular pathogens and neutralize toxins. The development, activation, and differentiation of B cells are tightly regulated by epigenetic mechanisms—including DNA methylation, histone m...

Shao-Cun Zhang, Yu Wang, Xin Min et al. · Signal Transduction and Targ... · 0 citations

Aug 2026

Nat10-mediated ac4C modification sustains macrophage proliferation and mitigates colitis progression via Mcm2 stabilization.

This study provides the first in vivo evidence that Nat10-mediated ac4C modification sustains macrophage proliferation and attenuates colitis progression by stabilizing Mcm2 mRNA.

Jin-Song Wang, Tao Liu, Jia-Cheng Zhao et al. · Science China Life Sciences · 0 citations