Central medial thalamic nucleus–targeted temporal interference stimulation promotes arousal: translational evidence from optimized preclinical models to patients with disorders of consciousness
Patients with disorders of consciousness (DoC) lack effective non-invasive neuromodulation therapies capable of targeting deep-brain arousal circuits. Temporal interference stimulation (TIS) offers potential for non-invasive deep brain targeting. However, its efficacy, optimal stimulation parameters, and underlyi...