Author

Yu Zhou

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Open access Jul 2026

Deficient early canonical BMP9-SMAD signaling and dysregulated macrophage microenvironment characterize the failure of bone healing in a critical-size defect model

Early loss of canonical BMP9-SMAD signaling disrupts the balance between immune cell recruitment and bone remodeling, contributing to the development of atrophic non-union in critical-size defects.

Kai Zhong, Yufei Shao, Yu Zhou et al. · Frontiers in Endocrinology · 0 citations