Open access
Oct 2026
Integrated transcriptomic, machine learning, and network pharmacology analyses reveal shared inflammatory biomarkers between intervertebral disc degeneration and osteoporosis
Intervertebral disc degeneration (IDD) and osteoporosis (OP) frequently coexist, but their shared inflammatory molecular features remain unclear. We investigated whether the two disorders share an immune-extracellular matrix axis and sought candidate inflammation-associated biomarkers. Public transcriptomic...
Meng-Jie Zheng, Gui-Zhi Zhu, Hong-De Jiang et al.
· Frontiers in Immunology · 0 citations