Author

Yuan Gao

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Open access Sep 2026

Discrete synaptic states and context-modulated readouts support continual learning

The Context-modulated Synaptic-states Recurrent Neural Network (CoSyn-RNN), a new continual-learning model inspired by heterogeneous synaptic states and neuro-modulatory control, is introduced, in which protected synaptic states, sparse allocation, and context-dependent modulation support continual learning.

Yuan Gao, S. Mihalas, Denis Turcu · bioRxiv · 0 citations

Open access Jul 2026

A consensus atlas of human brain development defines cell type-specific maturation trajectories across the lifespan

A consolidated cellular-resolution transcriptomic atlas of human brain development from the onset of neurogenesis to adulthood is presented, covering ∼2.2 million cells from 156 donors across nine studies, and dynamic gene programs predictive of cell-type maturation are identified.

Sridevi Venkatesan, Patricia R. Nano, Jonathan M. Werner et al. · bioRxiv · 0 citations