Author

Yuan-Hao Peng

2 papers indexed here

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Aug 2026

Adaptor AP4M1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis through USP15-mediated deubiquitination and MINK1-dependent phosphorylation.

It is shown that AP4M1 is markedly upregulated in HCC, correlates with unfavorable prognosis, and is functionally involved in driving HCC progression, providing a critical theoretical basis for AP4M1-targeted therapeutic strategies in HCC.

Yuan-Hao Peng, K. Kang, Xuanxuan Li et al. · Cancer Letters · 0 citations

Open access Aug 2026

Oncogenic USP3 promotes hepatocellular carcinoma progression via K11/K48-specific deubiquitination and stabilization of YAP

Summary Hepatocellular carcinoma (HCC) has a poor prognosis, necessitating therapeutic targets, while the role of ubiquitin-specific protease 3 (USP3) in HCC remains unclear. This study aimed to elucidate the function of the deubiquitinating enzyme USP3 in HCC. USP3 was found to be highly expressed in HCC tissues and a...

Yuan-Hao Peng, H. Nie, Xuanxuan Li et al. · iScience · 0 citations