Yuan-Hui Hu

Metal-sulfur metabolic derangement and regulated cell death in age-related cardiovascular diseases: mechanisms, biomarkers, and emerging interventions.

Cardiovascular ageing is accompanied by progressive impairment of redox buffering, mitochondrial quality control, proteostasis and metal homeostasis. Iron and copper homeostasis, together with cystine-glutathione and thiol/disulfide redox metabolism, are increasingly recognized as interconnected determinants of metabol...