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Yuankun Zhai

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Open access Sep 2026

Integrative Transcriptomics Reveals a Mitochondria-Related Gene Signature in Periodontitis

Mitochondrial dysfunction contributes to periodontal inflammation and tissue destruction, yet the mitochondria-related transcriptional changes associated with periodontitis remain incompletely characterized. Using an integrative bioinformatics study design with experimental validation in cellular and animal models, we...

Si-Yuan Wu, Miao-Miao Feng, Meng-Yao Liu et al. · 0 citations
Open access Jul 2026

Spatially resolved proteomics provides insights into the normal-dysplasia-tumor continuum in oral squamous cell carcinoma.

Spatially resolved proteomics of archived formalin-fixed paraffin-embedded tissues provides a morphology-anchored proteomic continuum of oral malignant transformation in a small spatially matched cohort, suggesting that OSCC progression involves early-shift, progressive, and transient dysplasia-specific programs.

Chaoran Peng, Xinjia Cai, Ming-Wei Huang et al. · 0 citations

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