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Review Sep 2026

Bone metastasis in cancer: from microenvironmental remodeling to precision therapy.

Bone metastasis remains a major determinant of disability, treatment failure, and poor survival in solid tumors. It is no longer adequately explained as a late consequence of tumor spread or as a process driven only by osteoclast-mediated bone destruction. Current evidence supports a broader view in which bone metastas...

Qin-Gan Feng, Xiu-Hai Ji, Qi Sun et al. · 0 citations
Review Sep 2026

IgG4 and Rheumatoid Arthritis: A Comprehensive Review of Its Role in Inflammation, Biomarker Potential, and Therapeutic Implications.

IgG4 may have a complex, context-dependent role in RA, potentially reflecting both immune dysregulation and compensatory anti-inflammatory responses, and its pathogenic mechanisms, clinical utility, and potential as a therapeutic target are reviewed.

Li Zhang, Hai-Li Shen, Yuan Li · 0 citations

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