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Author

Yuan-Quan Yang

2 papers indexed here

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Open access Nov 2026

Circulating Tumor DNA Clearance Is Associated with Response and Survival in Metastatic Urothelial Carcinoma Treated with First-Line Enfortumab Vedotin Plus Pembrolizumab

Background/Objectives: Enfortumab vedotin plus pembrolizumab (EV+pembro) is the standard first-line treatment for metastatic urothelial carcinoma (mUC), yet no validated on-treatment biomarker identifies patients deriving a durable benefit. We evaluated whether circulating tumor DNA (ctDNA) clearance is associated with...

Adam Khorasanchi, Sayan Mullick Chowdhury, E. Hong et al. · 0 citations
Open access Sep 2026

Temporal dynamics of the immune response to neoadjuvant androgen deprivation therapy suggest a window of opportunity for checkpoint inhibitor therapy in prostate cancer

The induction of a bi-phasic response in the TiME is revealed: robust CTL activation 3–5 months after nADT is initiated, followed by myeloid immunosuppression in tumors receiving prolonged nADT.

Anmbreen Jamroze, Ren-Yuan Zhang, Emily M. Dougherty et al. · 0 citations

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