Plasma proteomics is expanding across platforms and cohorts, and integrating these data for AI demands comparability at the protein level, not merely concordant associations1,2. Affinity and MS platforms use distinct probes (antibodies, aptamers, or peptides) and signal readouts, yielding contradictory cross-platform r...
The findings reveal that adaptive introgression can contribute to complex human adaptation through functionally convergent combinations of archaic variants, rather than only through shared large-effect haplotypes.
It is shown that high data quality and depth improved the accuracy of splice junction detection, as well as isoform- and event-level quantification and differential analysis, contributing to effective srRNA-seq application in RNA splicing research.
Duo Wang, Jia-Xin Zhao, Qing-Wang Chen et al.· Nature Communications· 0 citations
A novel deep learning framework based on Transformer, coined as TransNRank, that streamlines the prediction pipeline but also sets a new state-of-the-art for neoantigen discovery, with broad implications for accurate immuno-oncology.
Zhiyin An, Yue-Nan Hou, Shumeng Duan et al.· 0 citations
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