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Open access Sep 2026

Three‐Dimensional Collagen Microenvironment Activates NF‐κB/Stat3 Axis to Promote Cancer Chemoresistance and Partial EMT in Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) remains a leading cause of cancer mortality worldwide, with treatment resistance posing a major clinical challenge. The tumor microenvironment, particularly the three‐dimensional (3D) extracellular matrix architecture, plays a critical role in driving therapy resistance, ye...

Cui-Rong Gu, Long Li, Yu-Xin Gan et al. · 0 citations

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