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Yuan Wen

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Open access Aug 2026

Skeletal Muscle Stem Cell-Derived Myonuclei Adopt Divergent Terminal Transcriptional States in Adult and Aged Muscle In Response to a Hypertrophic Stimulus

By defining the age-associated fate of MuSC fusion to muscle fibers, it is provided potential targets for modulating muscle plasticity and predicts Runx1 may function as a master regulator of MuSC-Derived myonuclear specialization in response to MOV.

Nicholas T. Thomas, Jensen Goh, Kevin A. Murach et al. · 0 citations

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