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Review Sep 2026

Emerging biodegradable nanomaterials for innovative tumor immunotherapy.

Immunotherapy has rapidly emerged as the new pillar of cancer treatment alongside surgery, radiotherapy and chemotherapy. However, existing immunotherapeutic approaches face significant limitations such as inefficient tumor-targeted drug delivery, poor cellular internalization and off-target effects, all of which lead...

Ru-Tuan Dong, Shuai-Shuai Ding, Bo-Kai Song et al. · 0 citations
Aug 2026

In situ macrophage reprogramming via micropatch engineering for safe and effective antitumor adoptive cell therapy.

Adoptive cell therapy with macrophages holds great promise for treating solid tumors, but its clinical impact has been limited. The problem is twofold: the immunosuppressive tumor microenvironment quickly silences the anti-tumor activity of transferred cells, and systemic activation strategies often provoke off-target...

Yongkang Xu, Lei Cao, Yuyan Zhou et al. · 0 citations

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