Author

Yuanyuan Huang

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Oct 2026

Connection-Level Multi-Omics Reveals Cerebellar-Cortical Dysconnectivity and Divergent Molecular Signatures Across Major Psychiatric Disorders.

BACKGROUND Understanding how disease-related connectome alterations relate to underlying molecular systems remains a major challenge in psychiatric disorders. METHODS Here we introduce BrainNetAnno (https://brainnetanno.readthedocs.io/en/latest), an open-source framework for molecular annotation of brain network conn...

Yun-Heng Diao, Yuan-Yuan Huang, Bao-Yuan Zhu et al. · Biological Psychiatry · 0 citations

Sep 2026

Compensatory neurochemical adaptation in first-episode, drug-naïve depression: Integrating cortical and systemic metabolism using multivoxel 1H-MRS.

Findings suggest a possible compensatory neurochemical pattern associated with low BMI in depression, however, the cross-sectional design cannot determine whether this pattern reflects compensatory adaptation or a pre-existing neurobiological subtype, and low BMI alone should not be interpreted as evidence of metabolic...

Shu-Shu Huang, Feng-Chun Wu, Liang-Da Zhong et al. · Journal of Affective Disorde... · 0 citations

Open access Aug 2026

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

The results suggested that associations between proinflammatory gut microbiota and the herpes simplex virus type 1 infection pathway may contribute to the onset of MDD through inflammatory processes.

Wei Wang, Baoyuan Zhu, Yuanyuan Huang et al. · Interdisciplinary Medicine · 0 citations

Open access Jul 2026

Relationships of oxidative stress, inflammation and gut microbiota with cognitive impairment in first-episode major depressive disorders: a pilot study in China

The research showed that the GM and their predicted metabolic pathways in patients with MDD were closely related to cognitive function and peripheral blood indicators, and that differences in these factors may manifest as oxidative stress and inflammation.

He-hua Li, Baoyuan Zhu, Yuanyuan Huang et al. · Frontiers in Microbiology · 0 citations