Review
Open access
Oct 2026
Synergistic regulation of neuroinflammation by mitophagy and the cGAS–STING pathway following ischemic stroke
Neuroinflammation is widely recognized as a major driver of secondary brain injury following ischemic stroke. Recent studies have shown that mitochondrial dysfunction-induced mitochondrial DNA (mtDNA) release is one of the key mechanisms activating the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING)...
Yu Xiao, Pei-Jie Fu, C. Zhao et al.
· Frontiers in Molecular Neuro... · 0 citations