Yuan-Yuan Zhang

Screening the novel serum metabolites of vancomycin-induced acute kidney injury mice based on integrated metabolomics and transcriptomics.

Vancomycin-induced acute kidney injury (VANI-AKI) commonly occurs in critically ill patients. Current diagnosis relies on insensitive indicators such as serum creatinine (SCr) or oliguria, while the underlying molecular mechanisms remain unclear, hindering early detection and timely treatment. To identify novel metabol...