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Open access Oct 2026

Integrative Transcriptomic and Genetic Analysis Prioritizes IRF1 as a Candidate Regulatory Gene Associated with Ulcerative Colitis

Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with a complex and incompletely understood pathogenesis. This study aimed to prioritize candidate genes associated with UC and characterize their potential genetic and immune-related molecular context using an integrative transcriptomic and gene...

Yan-Yan Wang, Yue Chen, Hai-Lin Wu · 0 citations
Review Open access Sep 2026

Depressive symptoms as a mediator in the association between regular physical activity and irritable bowel syndrome-related symptom severity: a cross-sectional study among college students

Introduction Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, substantially affecting quality of life among young adults. Although regular physical activity (RPA) benefits both mental and gastrointestinal health, its potential psychological mechanisms in IBS-related symptom severity rema...

Y. Sui, Ping Li, Xian-Feng Yue et al. · 0 citations

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