Transcriptional reprogramming and epigenetic regulation in Paramecium caudatum: a new model for studying extreme germline DNA elimination.
Metazoans suppress transposons via small RNA-mediated silencing mechanisms, whereas ciliates have evolved a unique repressed strategy by physically eliminating transposons during somatic macronuclear genome development, offering unique models for transposon regulation and programmed DNA rearrangement. The ciliate Param...