Open access
Sep 2026
HIF1A+CSF3R+ neutrophils-dominated hypoxic niche induced metabolic reprogramming for neoadjuvant therapy resistance in NSCLC
Abstract Background Non-small cell lung cancer (NSCLC) is one of the frequently occurring cancers characterized by molecular heterogeneity and multiple immune cell infiltration patterns, which are associated with treatment sensitivity and resistance. However, the specific microenvironmental cells and their mechanisms t...
Yao-Yao Zhou, Zi-Yun Liu, Parhat Kaysar et al.
· Journal for ImmunoTherapy of... · 0 citations