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Open access Aug 2026

Original research Bifidobacterium breve LE4 Reduces Alzheimer's Disease Pathology and Confers Neuroprotection by Attenuating Neuroinflammation, Restoring Metabolism, and Preserving Gut Barrier

Emerging evidence implicates gut microbiota dysbiosis in Alzheimer's disease (AD) pathogenesis, suggesting probiotic interventions as a viable therapeutic strategy. This study systematically screened 18 Bifidobacterium strains, among which Bifidobacterium breve LE4 exhibited both potent antioxidant activity and lip...

Liu Yang, Yutian Huang, Meng-Ling Chen et al. · 0 citations
Review Open access Sep 2026

Probiotics For Depressive Symptoms: Gut–Brain Axis Mechanisms, Evidence, and Functional Food Translation

The prevalence of stress-induced mental health disorders, such as anxiety and major depressive disorder, is increasing globally. Growing evidence suggests that gut microbiota plays a crucial role in cognitive function and emotional regulation via the gut-brain axis. As a result, probiotics have emerged as a promisi...

Meng Tian, Liu Yang, Yue Li et al. · 0 citations

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