Visualizing and Targeting Tumor-Associated Neutrophils: Advanced Imaging, Therapeutic Reprogramming, and Cell-Based Delivery for Precision Oncology.
Tumor-associated neutrophils (TANs) are increasingly recognized as heterogeneous and context-dependent regulators of cancer progression and treatment response. Through cytokine secretion, protease release, oxidative activity, and formation of neutrophil extracellular traps (NETs), TANs remodel the tumor microenvironmen...