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Oct 2026

Epidermal growth factor receptor activation is associated with NSCLC cells resistance to ferroptosis and correlates with ROS-NRF2-GCLC/GCLM pathway activation.

Mutations of epidermal growth factor receptor (EGFR) closely correlate with differential ferroptosis sensitivity in select cell lines, but the underlying mechanism is poorly understood. In this study, we identified the epidermal growth factor (EGF)-activated EGFR as a correlate of ferroptosis suppression in non-small c...

Li Wang, Yu-Qing Wang, Yuan Li et al. · 0 citations
Open access Aug 2026

Clinicopathologic and prognostic value of HER2 alterations in non-small cell lung cancer

Human epidermal growth factor receptor 2 ( HER2 ) alterations represent emerging therapeutic targets in non-small cell lung cancer (NSCLC). However, the clinicopathological and prognostic values of HER2 mutations, amplification, and over expression remain poorly defined, leading to uncertainty in their prog...

Yicong Lin, Qian-Qian Xue, Bingxia Zhang et al. · 0 citations

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