Ultrasound/pH Dual-Responsive Cu-Zn-Based Microneedles for Piezo-Sonodynamic and Multimechanism Synergistic Induction of Cuproptosis and Ferroptosis.
Sonodynamic therapy is hindered by the insufficient catalytic activity of nanomaterials, the robust antioxidant capacity of the tumor microenvironment, and the limited targeting efficiency of conventional drug delivery systems. In this study, CuSn(OH)6 nanorods were synthesized via coprecipitation. These were then tran...