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Open access Jul 2026

Macrophage NPM1 drives anti-tumor immunity via the STAT3-CCRL2 axis

Background Although nucleophosmin (NPM1) is a well-characterized oncogene in acute myeloid leukemia, much less is known about its role in solid tumor immunity. Here, we examined the function of NPM1 in regulating anti-tumor immunity within the tumor microenvironment. Methods The proportion and functional changes of mac...

Lei Hong, Yue Yang, Yuwen Han et al. · 0 citations

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