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Author

Yue Zhang

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2 papers indexed here

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Open access Sep 2026

Targeting BIRC6 rejuvenates hematopoietic stem cell aging and immunosenescence

It is revealed that regulatory T cells within the bone marrow microenvironment actively safeguard the survival of aged HSCs via a previously uncharacterized signaling pathway, and targeted BIRC6 inhibition in HSCs using antibody-conjugated lipid nanoparticle-encapsulated antisense oligonucleotides (LNP-ASOs) significan...

Wei-Nian Liao, Fang-Ze Shao, Shao-Yan Wang et al. · 0 citations
Review Open access Aug 2026

Stem-like CD4 T cells in tumors: an emerging framework for antitumor immunity

Recent studies have identified antigen-experienced TCF1+PD-1+ lineage-negative (lin-) CD4 T cells in several tumor types. Strictly, stemness requires durable self-renewal and multipotent output demonstrated at the single-cell level; these criteria have not yet been established for an individual tumor-associated CD4 T c...

Jia-Xiang Xu, Yun-Chao Yang, Jun Zhang et al. · 0 citations

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