Aug 2026
MCART1 (SLC25A51) deficiency exacerbates mitochondrial dysfunction during MPP+-induced complex I stress.
It is shown that loss of MCART1 exacerbates mitochondrial dysfunction under physiological conditions, and that MCART1 contributes to maintaining membrane potential, preventing ATP depletion, and suppressing ROS accumulation in MPP+-treated neuronal cells.
Shi-Liang Wang, Pei-Xin Sun, Yue Zhang et al.
· Free Radical Biology & Medic... · 0 citations