Author

Yue Zhao

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Case report Open access Sep 2026

Case Report: Immunotherapy-containing fertility-sparing treatment integrated with preimplantation genetic testing resulting in live birth in Lynch syndrome-associated endometrial cancer

Background Lynch syndrome-associated endometrial cancer (LS-EC) presents unique challenges for fertility preservation. Conventional progestin-based therapy may be less effective in mismatch repair-deficient (MMRd) tumors, whereas immune checkpoint inhibitors (ICIs) have shown promising activity. Meanwhile, preimplantat...

Yan-Nan Zhao, Yue Zhao, Ting Hu et al. · Frontiers in Oncology · 0 citations

Review Open access Aug 2026

The role of NRG1 and its receptor HER3 in gastrointestinal tumors

Neuregulin 1 (NRG1), as a key ligand of the epidermal growth factor receptor family, plays a crucial role in the initiation, progression, and metastasis of various solid tumors by binding to human epidermal growth factor receptor 3 (HER3) and activating downstream signaling pathways. In recent years, NRG1 gene fusions...

Yue Zhao, Yuting Yong, Yuan-Shuai Li et al. · Cancer Plus · 0 citations