Open access
Aug 2026
Novel mitophagy activator TJ0113 restricts cytosolic mtDNA to suppress ZBP1-driven inflammation in acute lung injury
It is demonstrated that TJ0113, a novel mitophagy activator, confers protection against LPS-induced ALI by promoting mitochondrial quality control and limiting cytosolic mtDNA accumulation.
Xiao-Han Chen, Shun-Peng Xing, Xufeng Cen et al.
· Redox Biology · 0 citations