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Author

Yufei Du

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Open access Jul 2026

Manganese-Polydopamine Nano-Immunomodulator Synergistically Activates the STING Pathway and Pyroptosis for Renal Cell Carcinoma Immunotherapy 2308359

In vivo, PDA-Mn-HA NPs not only inhibited RCC tumor growth but also increased immune cell infiltration, particularly cytotoxic T cells, reshaping the tumor microenvironment to promote anti-tumor immunity.

Yiming Zhou, Yue Pan, Yufei Du · 0 citations
Open access Jul 2026

Antibody-mediated CAR T Platform for Targeting Tumor Cells and the Tumor Microenvironment 2301697

A dual-targeting strategy disrupted the TME-induced immune suppression, reduced collagen deposition, and boosted T cell activity, resulting in notable tumor growth inhibition and prolonged survival in both subcutaneous and orthotopic pancreatic cancer models.

Yiming Zhou, Jian-Chuan Wang, Yufei Du · 0 citations

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