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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yuhan Tan

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Open access Jul 2026

CACUL1 promotes hepatocellular carcinoma progression through enhanced tumor cell proliferation and macrophage-mediated immune suppression

CACUL1 functions as a dual-axis oncogenic driver in HCC through enhanced tumor cell proliferation associated with PI3K/AKT signaling and immune evasion via Notch1-dependent macrophage polarization, positioning it as a candidate prognostic biomarker and therapeutic target.

Xing Wang, Yuhan Tan, Ju Wang et al. · 0 citations

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