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Author

Yuji Ito

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Oct 2026

NGS-Guided Discovery of Cross-Reactive TfR1 VHH Antibodies with Distinct Brain Localization Profiles.

Antibody delivery across the blood-brain barrier (BBB) remains challenging. We combined phage display with next-generation sequencing (NGS)-guided clone sequence-diverse selection to identify transferrin receptor 1 (TfR1)-binding VHH antibodies. Following alpacas immunization with human and rat TfR1, representative clo...

Muhammad Feisal Jatnika, Asaki Nagashima, Wakana Miyahara et al. · 0 citations

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