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Author

Yujiao Chen

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Review Open access Jul 2026

Dynamic regulatory mechanism of cholesterol 25-hydroxylase-mediated antiviral response in RNA virus infections

This review comprehensively elucidated the dynamic molecular interactions between CH25H and RNA viruses, integrating recent research advances with a focus on molecular regulatory mechanisms and provided a mechanistic framework for understanding host–virus conflicts centered on cholesterol metabolism.

Zhengqi Liang, Simiao Xing, Yujiao Chen et al. · 0 citations
Jul 2026

Construction and systematic engineering of Saccharomyces cerevisiae for efficient de novo biosynthesis of pentostatin.

Pentostatin is a potent adenosine deaminase inhibitor, yet its industrial application is hindered by low extraction yields and complex chemical synthesis. Here, we report an efficient de novo biosynthesis platform for pentostatin in Saccharomyces cerevisiae. Starting with the heterologous expression of cns3 from Cordyc...

Ming-Zhe Bai, Zhiyi Liu, Chao-Zhong Wang et al. · 0 citations

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