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In controlled comparisons, wavenumber-based encoding outperformed index-based and learned encodings under partial observation and retained its performance on sampling grids never seen during training, where index-based encoding degraded.
RNA splicing is frequently disrupted by genetic variation, contributing to a wide range of human diseases. Identifying the variants responsible for altered splicing is therefore crucial but has long been challenging. Deep learning models that predict splicing from genomic sequence have substantially advanced their dete...
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