Efficacy of Nonopioid Analgesics (Acetaminophen and NSAIDs) Used Alone or in Combination with Opioids for Cancer Pain: Latest Updates on the Evidence Supporting the Guidelines.
Cancer pain significantly impairs patients' quality of life. Although the World Health Organization recommends nonopioid analgesics for pain management in this context, previous systematic reviews have been limited to the qualitative synthesis of oral formulations published up to 2017. To address these limitations and...