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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yuliang Huang

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Open access Aug 2026

ALKBH3 is an NPM1-dependent nucleolar protein required for rRNA biogenesis and translation.

The nucleolus is a membraneless nuclear organelle formed by liquid-liquid phase separation and serves as the hub for ribosomal RNA (rRNA) transcription and ribosome assembly. Here, we identify ALKBH3, a Fe(II)/α-ketoglutarate-dependent dioxygenase, as a previously unrecognized nucleolar protein that colocalizes with th...

Xixi Ma, Yuliang Huang, Hao Jin et al. · 0 citations

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