Long-alkyl-chain-modified near-infrared fluorescent probe for in vivo visualization of viscosity and ONOO- in inflammation.
BACKGROUND Rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) are prevalent immune diseases that pose substantial global public health burdens. Early, accurate molecular imaging of inflammatory biomarkers in situ remains a major challenge. RESULTS Herein, we rationally designed a novel near-infrared (NIR)...