Yun-Fei Zhan

PD-1 expression reprograms tumor-associated macrophages polarization and influences progression and clinical outcomes in lung adenocarcinoma.

BACKGROUND Programmed death-1 (PD-1) is critical in reprogramming tumor-associated macrophage (TAM) polarization and is associated with lung adenocarcinoma (LUAD) progression and prognosis. LUAD is the most common histological subtype of non-small cell lung cancer (NSCLC), but checkpoint blockade response rates remain...