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Open access Aug 2026

PDZ-binding kinase promotes ovarian cancer cell proliferation and invasion via CCNB1 regulation

Background Ovarian cancer is one of the most lethal gynecological malignancies, characterized by late diagnosis, frequent recurrence, and high mortality. PDZ-binding kinase (PBK), a serine/threonine kinase of the mitogen-activated protein kinase kinase (MAPKK) family, has been implicated in the tumorigenesis of multipl...

Guzhanuer Awuti, Jia-Po Wang, Yun Lu et al. · 0 citations

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