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Yun-Lu Zhao

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Open access Sep 2026

RAMP3 is associated with macrophage-driven immune exclusion and promotes resistance to PD-1 blockade in breast cancer: integrated in vivo and single-cell transcriptomic analyses

The results suggest that RAMP3 contributed to the establishment of an immunosuppressive TME and integration with human clinical datasets supports further investigation of RAMP3 as a potential therapeutic target for overcoming resistance to immune checkpoint therapy in breast cancer.

Yan Zhang, Megumu Tanaka, T. Sakurai et al. · 0 citations

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