Open access
Sep 2026
Genomic Characterization of ETV6::RUNX1-Positive Childhood B-ALL in a Chinese Cohort: Novel Fusion Partners, Co-Occurring Mutations, and Risk-Stratifying Biomarkers.
BACKGROUND ETV6::RUNX1 is the most common genetic abnormality in pediatric B-cell acute lymphoblastic leukemia (ALL; ∼25%), yet the comprehensive genetic architecture and molecular predictors of intermediate-risk (IR) stratification remain incompletely characterized. METHODS We performed whole-transcriptome sequencin...
Hua-Lei Luo, Gui-Chi Zhou, Qian Li et al.
· Pediatric Blood & Cancer · 0 citations