Author

Yun Wang

2 papers indexed here

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Sep 2026

A Metabolic Nanoplatform Potentiates Triple-Negative Breast Cancer Radiosensitivity via Disrupting Carbonic Anhydrase IX/Pentose Phosphate Pathway Crosstalk

Radiotherapy resistance in tumors driven by metabolic adaptations within acidic microenvironments involves the upregulation of both carbonic anhydrase IX (CA IX) and the pentose phosphate pathway (PPP) as well as the functional crosstalk between them. To overcome this, we developed a polyvinylpyrrolidone (PVP)-modifi...

Zhi-Li Ma, Bin Zhao, Yun Wang et al. · ACS Nano · 0 citations

Review Open access Aug 2026

Zinc-based nanoplatforms for cancer immunotherapy achieved through the cyclic GMP-AMP synthase-stimulator of interferon genes pathway: Bridging tumor metabolism and immune activation.

How tumor-responsive Zn²⁺ release, oxidative stress, DNA damage, and metabolic remodeling collectively enhance antitumor immunity is highlighted.

Yi-Zi Wang, Yu-Tao Wang, Cheng Zhang et al. · Acta Biomaterialia · 0 citations