Author

Yun-Xiu Wang

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Review Jul 2026

Dual role of macrophage heterogeneity in allergic inflammation: from mechanism to targeted therapy.

Allergic inflammation, such as allergic asthma, allergic rhinitis, and atopic dermatitis, shares many pathogenic hallmarks, including inappropriate activation of type 2 immune responses, tissue barrier dysfunction, and disruption of local homeostasis. Due to their remarkable plasticity and tissue adaptability, macropha...

Guijie Yuan, Meng Wang, Zhiwei Cao et al. · International Immunopharmaco... · 1 citation

Review Open access Jul 2026

Macrophage autophagy in allergic diseases: Regulatory mechanisms, immune crosstalk, and therapeutic implications.

This review systematically synthesizes the molecular mechanisms governing macrophage autophagy and its dual role in allergic diseases, and summarizes potential therapeutic strategies targeting macrophage autophagy, such as budesonide/simvastatin combination therapy and rapamycin derivatives, along with their clinical t...

Kaihang Fan, Zhaowei Gu, Yunxiu Wang · International Immunopharmaco... · 0 citations