Author

Yun Yang

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Open access Oct 2026

DIA Quantitative Proteomic Analysis Reveals Early Proteomic Responses to Honeybee-Derived Melittin in Murine Breast Cancer Cells

Breast cancer remains a major clinical challenge because of its molecular heterogeneity, therapeutic resistance, and disease recurrence. Melittin, the principal bioactive peptide of honeybee venom, exhibits antitumor activity in multiple experimental models; however, its early proteome-wide effects in breast cancer cel...

Jun-Ling Zhu, Wen-Hua Xu, He Zang et al. · Biology · 0 citations

Open access Aug 2026

Melittin intervention induces lncRNA response, mitochondrial dysfunction, and cell proliferation in murine cervical cancer cells

Melittin exhibits antitumor activity in cervical cancer models, yet the long non-coding RNA (lncRNA) response and associated regulatory networks remain poorly understood. Here, strand-specific RNA-seq data from melittin-treated and untreated U14 murine cervical cancer cells were analyzed to characterize melittin-respon...

Ronghua Zhang, Haiwen Zhuo, Yun Yang et al. · bioRxiv · 0 citations

Open access Aug 2026

LncRNA6470/ace-miR-750-y axis modulates AcPP2A gene, immune response and survival of eastern honey bee larvae during fungal infection

ABSTRACT Chalkbrood, a destructive larval disease caused by the fungal pathogen Ascosphaera apis, causes substantial losses in apiculture. Although host–pathogen interactions in Apis mellifera larvae infected with A. apis have been investigated, immune defense mechanisms in the Asian honey bee Apis cerana remain unclea...

Xiaoxue Fan, Kaiyao Zhang, Yun Yang et al. · Virulence · 0 citations