α-Cyperone targets the PAK1-JNK/NF-κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model
Asthma is a common chronic airway inflammatory disease affecting millions of patients worldwide, and its treatment remains a clinical challenge. A variety of immune cells, cytokines and inflammatory mediators are associated with asthmatic pathogenesis. The α-Cyperone (CYP) is the active ingredient of Cyperus rotundus L...