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Review Open access Oct 2026

TGF-β in chronic kidney disease: a controversy for decades

Chronic kidney disease (CKD) is characterized by persistent inflammation, maladaptive repair and progressive renal fibrosis, yet therapeutic strategies capable of effectively targeting these interconnected processes remain limited. Transforming growth factor-β1 (TGF-β1) is a central mediator of renal fibrosis but also...

Heng Wang, Jie Tian, Guo-Ping Zheng et al. · 0 citations

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