Open access
Sep 2026
DNA polymerase I is required for the Hachiman-family anti-phage defense system
ABSTRACT Abortive infection (Abi) systems protect bacterial populations from bacteriophages by triggering growth arrest or cell death in infected cells; however, how Abi effectors are coupled to changes in host DNA replication and repair remains unclear. The widely conserved Hachiman defense system encodes a nuclease (...
Saya Takita, Reoto Moroi, Haruka Terasaki et al.
· Journal of Bacteriology · 0 citations